Logo

A Laboratory Manual of Physical Pharmaceutics is introduced to the B.Pharm students for easy understanding of the principles of physical pharmaceutics. The Experimental manual covers experiments to provide fundamental principles of physical pharmacy necessary to design physically and chemically stable dosage forms and ensure their therapeutic safety and efficacy. This manual is a unique in nature as it covers the two necessities of students: text on theoretical principles and its application including illustrative exercises in the form of practical.

· This Book illustrates all the experiments included in various Universities syllabus of physical pharmacy.

· It also provides an integrated understanding of theory and practical applications associated with physicochemical concepts in a very lucid language.

· Reviews the physico-chemical concepts in the design of various dosage forms.

· Provides several experiments related to physical chemical characteristics of any dosage forms.

· Useful to teachers also.

Contents: I. Basic Rules and Requirements: 1. Pharmaceutical Microbiology and Basic Rules of Laboratory. 2. Basic Requirements of Microbiology Laboratory Instrumentation. 3. Microscope. 4. Autoclave. 5. Incubator. 6. Hot Air Oven. 7. Laminar Air Flow. 8. pH Meter. 9. Spectrophotometer. 10. Colony Counter. II. Preparation of Culture Media, Sterilization and Culture Methods: 11. Preparation and Sterilization of Media. 12. Aseptic Technique and Transfer of Microorganisms. 13. Growth Promotion Test of the Medium. 14. Preparation of Agar Slants, Stabs and Plates. 15. Preservation of Microbial Cultures : Techniques for Isolation of Pure Culture from Mixed Culture. 16. Streak Plate Method. 17. Pour Plate Method. 18. Spread Plate Technique. III. Staining Techniques of Microorganisms: 19. Preparation of a Bacterial Smear. 20. Staining. 21. Simple Staining. 22. Negative Staining. 23. Gram Staining. 24. Acid-Fast Staining. 25. Staining of Fungus by Lactophenol Cotton Blue. IV. Biochemical Tests for Identification of Bacteria: 26. IMViC Tests. 27. Indole Test. 28. Methyl Red and Voges-Proskauer Test (MR-VP Test). 29. Citrate Test. 30. Carbohydrate Fermentation Test. 31. Starch Hydrolysis Test. 32. Gelatin Hydrolysis Test. 33. H2S Production Test. V. Bacterial Motility: 34. Wet Mount Method. 35. Hanging Drop Method. 36. Soft Agar and Agar Deep Tube Methods. VI. Microbial Assay of Antibiotics: 37. Microbial Assay of Antibiotics. 38. Turbidimetric or Tube Assay Method. VII. Sterility Testing of Pharmaceuticals: 39. Sterility Testing of Pharmaceuticals. VIII. Environmental Monitoring: 40. Environmental Monitoring by Settling Plate Method Bacterial Analysis of Water. 41. Bacterial Examination of Water by Multiple Tube Fermentation Test.42. Bacteriological Examination of Water by Membrane Filtration Method. 43. Analysis of Water for Total Bacterial Population by Standard Plate Count. Microbial Taxonomy. 44. Fungi. 45. Bacteria.