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The “Compendium of Crop Improvement Volume 4: Plant Biotechnology” offers a comprehensive overview of the latest advancements and applications in the field of plant biotechnology, highlighting its transformative potential in modern agriculture. This volume is designed to provide an in-depth understanding of various biotechnological innovations, from genome editing techniques to bioinformatics and synthetic biology. With a focus on practical applications, the book explores how cutting-edge technologies like CRISPR/ Cas9, nanotechnology, and artificial intelligence are revolutionizing crop improvement and agricultural sustainability. The volume also delves into the critical role of biotechnology in addressing pressing agricultural challenges, including enhancing crop resilience to climate change, improving plant health through microbial biotechnology, and developing biofortified crops to combat malnutrition. The integration of omics approaches, precision agriculture, and plant-microbe interactions showcases the multidisciplinary nature of modern plant biotechnology and its impact on the future of food security and environmental sustainability. The book serves as a valuable resource for students, researchers, and professionals in the field of plant sciences, offering insights into both the theoretical and practical aspects of plant biotechnology. By covering emerging trends, such as biopharming, metabolic engineering, and disease management, this volume provides readers with a forward-looking perspective on how biotechnology can shape the future of agriculture and contribute to global sustainability efforts.