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The book “Aflatoxicosis in animals and its public health significance” has been prepared to give an insight of aflatoxins and the economically important animal disease it produces – the aflatoxicosis. This book encompasses from the very basic understanding of aflatoxicosis to the recent advances and latest generation tools for its detection and detoxification, suitable prevention and control strategies to be adopted, along with its epidemiological, economical and public health significance. To give additional advantage to the students, model questions along with the key for self assessment have been included at the end of the book. This book provides a systemic approach to understand aflatoxicosis and necessary protocols and methodologies for the detection of aflatoxins have been incorporated. The book will be very helpful for the researchers, veterinarians, students and persons involved in the service and welfare of animal and human diseases.