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This book aims to help the student bridge the gap between the classroom and clinical practice; introducing the automation principles in hematology along with interpretation and deciphering of various parameters like RDW and histograms which carry a lot of encrypted diagnostic information, because eyes can see only those things which brain knows. Although the data of the automated blood count alone will not guarantee a specific diagnosis in every case, nor does every disease have a single pattern of abnormality, rather these values should be used to narrow the differential diagnosis as much as possible, so that more expensive and time requiring, confirmatory battery of expensive investigations like Vitamin B12, folic acid, serum iron, TIBC estimations or Hb electrophoresis, etc. is done only selectively and invasive procedures like bone marrow aspiration and biopsy can be avoided, by proper evaluation of CBC.